Clinical Genomics Uppsala frequently engages in collaborative projects with industry and academia. Our contribution to these partnerships can for example include:
- Development of novel diagnostic methods
- Testing of new products
- Characterization of patient material
Examples of past and current collaborative projects
Gene panels and software evaluation
We have evaluated two SureSelect panels (CPP17 and Human All Exon 7) and the Alissa Align and Call software platform on clinical samples.
Tumor mutation burden in solid tumors
In collaboration with Bristol-Myers Squibb and Illumina, we have evaluated broad gene panels that allow calculation of tumor mutation burden (TMB) in solid tumors. A high TMB is a biomarker for patients likely to respond well to immunotherapy.
Resistance mutation testing in leukemia
We collaborate with Incyte and several European laboratories to standardize and establish NGS-based resistance mutation testing in leukemia. We take part in a Nordic study aiming to monitor mutations in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL).
Please contact us if you are interested in initiating a new collaborative project with us.